Author(s):

Shovon Lal Sarkar, Prianka Saha and Nigarin Sultana

Abstract: Tridax procumbens Linn. is renowned for its traditional use as ayurveda in folk medicine all over the world. In this study, the plant was screened to ascertain its bioactive compounds and to determine the antimicrobial activity against different pathogenic microorganisms. Methanolic extract of the leaves of T. procumbens L. was examined at different concentrations on both bacteria and fungi by disc diffusion method and agar well diffusion method. Both gram positive and negative bacteria including E. coli, V. cholera, B. subtilis, B. cereus and S. aureus showed sensitivity to 250 µg/ml and 500 µg/ml plant extract except Salmonella typhi was resistant to both concentrations. Their zone of inhibition was within 8-14mm range in diameter for both concentrations. Several fungal species including C. albicans, A. niger and A. fumigatus were also tested for its susceptibility to methanol extract and showed significant value within the range of 9-15mm zone of inhibition with great potency against C. albicans. MIC and MFC was also determined at different concentrations to evaluate the efficacy of methanol extract. The findings of current study suggested that T. procumbens L. can be used as a potential source of alternative drugs in present days to combat the drug resistance phenomenon of different microorganisms.

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