Author(s):

Etou Ossibi AW, Morabandza CJ, Nsonde Ntandou GF, Tsala D, Elion Itou RDG, Ouamba JM and Abena AA

Abstract: Oxidative stress is currently accused in the release and the progression of several diseases. In the present study, the effect of aqueous extract of the leaves of Lippia multiflora Moldenke on oxidative stress induced by the DOCA-salt and hydrogen peroxide was studied respectively in rat and mouse. The results obtained show that aqueous extract reduced diminution of catalase activity, GSH and NO contain and augmentation of MDA in rats DOCA-salt treated. The extract also significantly reduce (p<0,001) the concentration of hydrogen peroxide in rat leukocyte cells. These results suggest that aqueous extract of the leaves of L. multiflora Mold. have antioxidant potentiality which could contribute to the prevention or the treatment of several diseases.

Pages: 254-258  |  3641 Views  1764 Downloads

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