Journal of Pharmacognosy and Phytochemistry
Vol. 5, Issue 6 (2016)
Comparative antipyretic activity of ethanolic extracts of some species of Cynodon in rabbits
Abdul Baquee Ahmed, Dippriya Das and Rupa Sengupta
To investigate and compare the antipyretic activity of the Ethanolic extracts of Cynodon dactylon
and Cynodon barberi
in rabbits. The antipyretic activity of Ethanolic extract at a dose of 400 mg/kg and 600 mg/kg was tested be milk induced pyrexia in rabbits. Paracetamol (100 mg/kg) was used as standard drug and control group received distilled water. Rectal temperature of the rabbits was recorded till 4 hrs at an interval of 1 hr using digital thermometer. The investigation showed that the 600 mg/kg dose of both the drug showed a reasonable decrease in temperature (p
<0.05) when compared to the standard drug. The result showed that the Ethanolic extract of two species of Cynodon
possess significant antipyretic effect in maintaining reducing the milk induced elevated body temperature in rabbits and their effect were comparable to that of the standard antipyretic drug paracetamol.
Pages: 361-365 | 1212 Views 49 Downloads
Abdul Baquee Ahmed, Dippriya Das and Rupa Sengupta. Comparative antipyretic activity of ethanolic extracts of some species of Cynodon in rabbits. J Pharmacogn Phytochem 2016;5(6):361-365.