Journal of Pharmacognosy and Phytochemistry
Vol. 6, Issue 1 (2017)
Evaluation of antihypertensive activity of Sumbul-ut-Tib (Nardostachys jatamansi) in adrenaline induced dogâ€™s blood pressure
Mohd. Ashfaque, Nisar Ahmad, Zaheda Begum and Faizana Nasreen
Sumbul-ut-Tib has been used in Unani System of medicine since the time of Avicenna. He has described Jatamansi as one of the important cardiac drug in his book â€œAdvia Qalbiaâ€. The aim of this study was to determine the antihypertensive activity of Nardostachys jatamansi in dogâ€™s blood pressure which is induced by adrenaline.
Materials and Methods: Antihypertensive activity of ethanolic extract of Sumbul-ut-Tib at the doses of 10 mg/kg. b.wt, 20 mg/kg b.wt. and 25 mg/kg b.wt. against adrenaline at the dose of 1 mcg/kg b.wt. in dogs.
Results: The test drug produced fall in B.P. was noted, fall in B.P. was same in doses of 10 mg/kg. b.wt, 20 mg/kg. b.wt, while with the dose of 25 mg/kg. b.wt. more fall in B.P. was noted i.e. 160 mm of Hg to 130 mm of Hg.
Conclusion: This result suggests that the jatamansi revealed hypotensive activity against adrenaline induced hypertension.
Pages: 93-95 | 1512 Views 59 Downloads
Mohd. Ashfaque, Nisar Ahmad, Zaheda Begum and Faizana Nasreen. Evaluation of antihypertensive activity of Sumbul-ut-Tib (Nardostachys jatamansi) in adrenaline induced dogâ€™s blood pressure. J Pharmacogn Phytochem 2017;6(1):93-95.