Journal of Pharmacognosy and Phytochemistry
Vol. 6, Issue 1 (2017)
Phytochemical and biological investigation of the red sea marine sponge Hyrtios sp
Nourhan Hisham Shady, Usama Ramadan Abdelmohsen, Safwat Ahmed, Mostafa Fouad and Mohamed Salah Kamel
Three compounds including indole-3- carbaldehyde (1) 5, 6-dibromoindole- 3-carboxaldehyde (2) and Ergosterol (3) were isolated from Red Sea sponge Hyrtios
sp. The structures of compounds 1-3 were determined by spectroscopic analyses including 1D and 2D NMR, and HR-ESI-MS experiments as well as comparison to literature. These results demonstrate that sponges are rich sources for natural products with new pharmacological activities and relevance to drug discovery, some biological investigations were carried out to the total extract and some fractions of Hyrtios
sp as anti-inflammatory, anti-pyretic, analgesic activities and showed that the sponge Hyrtios
has significant biological activities.
Pages: 241-246 | 1735 Views 115 Downloads
Nourhan Hisham Shady, Usama Ramadan Abdelmohsen, Safwat Ahmed, Mostafa Fouad and Mohamed Salah Kamel. Phytochemical and biological investigation of the red sea marine sponge Hyrtios sp. J Pharmacogn Phytochem 2017;6(1):241-246.