Journal of Pharmacognosy and Phytochemistry
Vol. 6, Issue 1 (2017)
Wound healing effect of methanolic flower extract of Bauhinia tomentosa Linn. with emu oil in rats
R Ratna Manjula, Spandana Uppuluri, T Joshi Anand, V Adilakshmi, Pratyusha Gandrapu and Alekya Munagala
To investigate the wound healing property of methanolic flower extract of Bauhinia tomentosa with emu oil.
Method: Male Wister albino rats (n = 25) were used in this study. Excision wounds were created on the skin of five groups of 5 rats using surgical blade under anesthesia. The first group was topically treated with Vaseline alone, group 2 was topically treated with standard i.e., Soframycin ointment, group 3 was treated with Bauhinia flower extract alone, group 4 was treated with Emu oil alone and group 5 was treated with combination of Bauhinia flower extract and Emu oil.
Results: The phytochemical analysis revealed several bioactive constituent including carbohydrates, flavonoids, saponins, tannins & phenolic compounds, proteins and amino acids, gums and mucilage. The extract had significant (ANOVA, P<0.05) healing effect on the excision wounds.
Conclusions: These data indicates that Bauhinia tomentosa flower extract with emu oil contains potent bioactive compounds containing wound healing activity. Bauhinia tomentosa is substantiating its use as a wound healer.
Pages: 247-253 | 2075 Views 435 Downloads
R Ratna Manjula, Spandana Uppuluri, T Joshi Anand, V Adilakshmi, Pratyusha Gandrapu and Alekya Munagala. Wound healing effect of methanolic flower extract of Bauhinia tomentosa Linn. with emu oil in rats. J Pharmacogn Phytochem 2017;6(1):247-253.