Journal of Pharmacognosy and Phytochemistry
Vol. 6, Issue 2 (2017)
Standardization of marketed cystone tablet: A herbal formulation
Kiran A Wadkar, Manish S Kondawar and Sachin G Lokapure
The Present study aims to standardize Cystone tablet based upon chromatographic and spectral studies. The spectral data and HPTLC fingerprint of ethanolic extract of Cystone formulation could be used as a valuable analytical tool in the routine standardization of tablet to check the batch to bath variation. The ethanolic extract of Cystone tablet were compared by TLC, HPTLC and HPLC analysis to evaluate the presence of catechin employing Toluene: Ethyl acetate: acetone (2:4:4 v/v/v), as a mobile phase respectively. The Rf values (0.80) for catechin in both sample and reference standard were found comparable under UV light at 366 nm respectively. The high performance thin layer chromatography method developed for quantization was simple, accurate and specific.The present standardization provides specific and accurate tool to develop qualifications for identity, transparency and reproducibility of biomarkers catechin tablet formulation.
Pages: 10-16 | 1543 Views 93 Downloads
Kiran A Wadkar, Manish S Kondawar and Sachin G Lokapure. Standardization of marketed cystone tablet: A herbal formulation. J Pharmacogn Phytochem 2017;6(2):10-16.