Investigation of 70% aqueous methanol of Thunbergia grandiflora
Roxb leaves extract (Family Acanthaceae) led to isolation of ten compounds; Caffeic acid (1),
rhamnopyranoside (2), Kaempferol-3-O
-arabinopyranoside- 4'-methyl ether (3), Kaempferol-6-C-sophoroside (4) Kaempferide 3-O
- É‘-L-arabinofuranoside (5), Kaempferol-3-O
-Î±-L-rhamnopyranoside (6), isoquercetrin (7), Quercetrin (8), Quercetin (9) and Kaempferol (10) for the first time. The isolated compounds were identified by using
spectroscopic techniques as
C-NMR. Aqueous methanol extract of Thunbergia grandiflora
Roxb leaves exhibited marked hypoglycemic activity comparable to metformin as reference drug and antioxidant activity that was evaluated by glutathione and DPPH radical scavenging activity methods in comparison with vitamin E, as well as hepatoprotective effect to liver damaged rats using CCl4
and compared with silymarin as reference drug.
Magda T Ibrahim, Salwa A Abu El wafa, Amany A Sleem. Phytochemical and Biological Investigation of Thunbergia grandiflora. J Pharmacogn Phytochem 2017;6(2):43-51.