The results showed that the methanol and ethyl acetate extracts are endowed the best antibacterial effect against Staphylococus aureus and Aspergilus niger. Moreover, the methanol extract presented the strongest inhibitory potential against alpha-amylase (86.36%) with low levels of inhibition lipase activity. Meanwhile, this extract was found to have the highest phenolic content. Our study also showed that there were positive relationship among total phenolic contents and biological activities.

It was noticed that the extents of antibacterial, antidiabetic and antiobesity activities of Dictyopteris polypodioides extracts are in accordance with their phenolic compounds.