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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 6, Issue 3 (2017)

Evaluation of anti-diarrhoeal activity of Curcuma zedoaria rhizome

Author(s):

Md. Golam Azam, Md. Shibly Noman and Md. Adit Muktadir Pavel

Abstract:

Curcuma zedoaria (family: Zingiberaceae) is broadly used as a folk medicine in dyspepsia, cough, dermatosis, inflammations, diarrhoea and other diseases. In the present study, ethanol extracts of Curcuma zedoaria rhizomes was evaluated for phytochemical screening and antidiarrhoeal activity. The results showed that Curcuma zedoaria extract dose-dependently reduced the severity & frequency of diarrhoea in mice compared with the standard antimotility drug loperamide. Preliminary phytochemical screening of ethanol extract showed the presence of tannins, flavonoids, saponins, alkaloids, terpinoids, carbohydrates and steroids as major constituents, some of which possess antidiarrhoeal activity and justify the traditional use of the plant extract in the treatment of diarrhea.

Pages: 171-173  |  1312 Views  95 Downloads

How to cite this article:
Md. Golam Azam, Md. Shibly Noman and Md. Adit Muktadir Pavel. Evaluation of anti-diarrhoeal activity of Curcuma zedoaria rhizome. J Pharmacogn Phytochem 2017;6(3):171-173.