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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 6, Issue 4 (2017)

Spectrum of biological properties of cinchona alkaloids: A brief review

Author(s):

Pranay Gurung and Puspal De

Abstract:

Cinchona which belongs to family Rubiaceae, got its importance from the centuries because of its anti-malarial activity. Alkaloids present in this herb, Quinine, Chichonine, Quinidine and Cinchonidine are the main, but percentage may vary in species to species. Since the early 17th century, these alkaloid are frequently used in Indian ayurvedic, sidha and traditional folk medicine to treating fever and Still now in modern medicine cinchona alkaloids are used for the treatment of malaria as well as for other diseases and became the well-known drug after the treatment of malaria caused by Plasmodium Sp. Literature study revealed that along with the antimalarial activity the cinchona alkaloids has other potentiality like anti-obesity, anti-cancer, anti-oxidant, anti-inflammatory, anti-microbial activity. These article reviews the biological activities of cinchona alkaloids along with its toxic effect.

Pages: 162-166  |  1702 Views  279 Downloads

How to cite this article:
Pranay Gurung and Puspal De. Spectrum of biological properties of cinchona alkaloids: A brief review. J Pharmacogn Phytochem 2017;6(4):162-166.