Author(s):
Vawazola Nsimaketo Victor Héritier, Dani Nzizidi Arthur, Malumba Mukaya Augustin, Ngombe Kabamba Nadège, Kizungu Vumilia Roger, Sumbu Zola Lezi Pierre Eric et and Masimango Ndyanabo Jude-Thaddée
Abstract:
This work aimed to highlight antibacterial and antiplasmodial potentials of
Zingiber officinalis and
Monodora myristica essential oils. The extraction yields in essential oils were 1.28±0.05% for
Z. officinalis rhizome and 1.52±0.14% for
M. myristica seeds. Diameter of the inhibition zone formed as a result of
Z. officinalis oil is 39.17±1.44 mm, 37.00±4.33 mm, 36.17±6.64 mm and 20.67±2.26 mm respectively for
Salmonella sp, Pseudomonas aeruginosa, Klebsiella pneumoniae and
Staphylococcus aureus strains; for
M. myristica oil, 11.00±1.00 mm, 7.83±2.75 mm, 7.67±1.53 mm and 6.00±0.00 mm; and for eugenol used as control, 18.5±1.32 mm, 18.83±1.04 mm, 18.50±0.5 mm and 20.17±3.25 mm. The MIC of
Z. officinalis oil is 0.25% on
Salmonella sp, Klebsiella pneumoniae and
Staphylococcus aureus strains and 0.5% on
Pseudomonas aeruginosa strain; the MIC of
M. myristica oil is 0.1% on
Salmonella sp and
Staphylococcus aureus strains, 0.25% on
Pseudomonas aeruginosa strain and 0.5% on
Klebsiella pneumoniae strain and it is 0.05% for eugenol on all bacterial strains. The MBC of
Z. officinalis oil is 0.5% on
Staphylococcus aureus strain, 1% on
Salmonella sp and
Klebsiella pneumoniae strains and higher than 3.5% on
Pseudomonas aeruginosa strain; the MBC of
M. myristica oil is higher than 3.5% on all strains; for eugenol, the MBC is 0.1% on
Staphylococcus aureus strain and 0.5% on
Salmonella sp, Pseudomonas aeruginosa and
Klebsiella pneumoniae strains.
Z. officinalis oil has a bactericide action on
Salmonella sp, Klebsiella pneumoniae and
Staphylococcus aureus strains and a bacteriostatic action on
Pseudomonas aeruginosa strain;
M. myristica oil has a bacteriostatic action on all bacterial strains.
Z. officinalis oil make total inhibit completely trophozoites up to the concentration less than 6.25μg.mL
-1 while
M. myristica oil make total inhibit completely trophozoites up to the concentration of 12.5μg.mL
-1 and below this concentration, inhibition become partial.
Vawazola Nsimaketo Victor Héritier, Dani Nzizidi Arthur, Malumba Mukaya Augustin, Ngombe Kabamba Nadège, Kizungu Vumilia Roger, Sumbu Zola Lezi Pierre Eric et and Masimango Ndyanabo Jude-Thaddée. Antibacterial and antiplasmodial potentials of essential oils from two plants of Tangawisi products: Zingiber officinalis Roscoe and Monodora myristica (Gaertn) Dunal. J Pharmacogn Phytochem 2018;7(1):643-648.