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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 7, Issue 3 (2018)

HPLC quantification of andrographolide in different parts of Andrographis paniculata (Burm.f.) Wall. ex Nees

Author(s):

Seema Sharma, Yash Pal Sharma and Chitra Bhardwaj

Abstract:
Andrographis paniculata, a member of family Acanthaceae commonly found in plains of India, Pakistan and Sri Lanka and is an important medicinal plant, which is used in diseases like fevers, jaundice, colic dysentery and dyspepsia and also act as hepatoprotective, bitter tonic, stomachic, immunostimulant, antidote, antimalarial agent etc. The medicinal value of the plant is mainly due to active components as andrographolide, deoxy-andrographolide, neoandrographolide etc. present in the species. In the present study andrographolide, a major diterpenoid in Andrographis paniculata was quantified in different parts of plant using HPLC. The leaves were found to contain the highest content of andrographolide. The content ranged from 0.054 – 4.686%. The other parts studied were stem, flowering tops and roots. The andrographolide was detected in all four parts of the plant.

Pages: 168-171  |  2939 Views  1489 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Seema Sharma, Yash Pal Sharma and Chitra Bhardwaj. HPLC quantification of andrographolide in different parts of Andrographis paniculata (Burm.f.) Wall. ex Nees. J Pharmacogn Phytochem 2018;7(3):168-171.

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