Author(s):

Navadkar DT and Dilpak SA

Abstract: The medicinal plants represents an enormous reservoir of potential antimicrobial compounds that could be useful as an alternative to synthetic microbicides and these are being used to develop drugs. In current study, the antimicrobial activity of various leaf extract were estimated by disc diffusion method. The results of antimicrobial activity of all the extracts showed good inhibitory activity against all the tested microbes.Total four different medicinal plants namely tulsi, neem, castor & aloe vera leaf samples were collected from shree sai aurvedic research center, virag, district solapur to study synthesis of silver nanoparticles and antimicrobial activity from medicinal leaf extracts. Silver nano particles were synthesized by chemical reaction using methanol in 5% DMSO reagent. Lowest Optical Density measured by spectrophotometer at 300 nm which was 0.00 however highest Optical density recorded t 400nm by neem plant extract with silver nanoparticles which was 2.96 than other extracts. The silver nano particle synthesized by using medicinal plants extracts were assured for their antimicrobial activity against fungal and bacterial pathogen viz., E.coli, Pseudomonas, Staphylococcus, Bacillus and Aspergillus niger The primary screening of silver nano particles was done using disc diffusion method. In this view study was conducted to synthesize silver nano particles from medicinal plant extracts and its antimicrobial activity.

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