Author(s):

Madhu Kushwaha and Dr. Salendra Narayan

Abstract: Solanum virginianum (Family: Solanaceae) commonly known as the Indian night shade or Yellow berried night shade (English) and kantakari (Sanskrit). It is a prickly diffuse, bright green perennial herb, woody at the base, 2–3 m height, found throughout India, mostly in dry places. Solanum virginianum has as expectorant and antipyretic activities. The methanolic extract of leaves of Solanum virginianum is administered orally to a group of experimental animals at one of the defined doses such as 5, 50, 500, 2000mg/kg. There was no sign of toxic effect in dose between 5, 50, 300mg/kg. When the dose of 2000 mg/kg given to the animal, the toxic effect on animal was found such as low breathing, itching, swallowing and mortality. Then, 1/3 of the dose has been selected which is 100 mg/kg. The anti-inflammatory activity was evaluated using carrageenan induced paw edema models in wistar albino rats. The anti- inflammatory activity was found to be dose dependent in carrageenan-induced paw edema model. The results of present study demonstrate that methanolic extract of the leaves of Solanum virginianum possess significant (P < 0.05). The amount of the plants which have been asserted to possess anti-inflammatory effect is so much that evaluating all of them are out of the scope. Herbal medicine is one of the most important aspects of complementary medicines. There are many studies which have been asserted the role of several herbs in inflammation remission.

Pages: 3305-3311  |  1244 Views  487 Downloads

Download (938KB)