Author(s):

Dr. R Ganesan, R Nithya, B Nandhini, Dr. R Shakila, A Rajesh, F Mahesh and Dr. P Sathiyarajeswaran

Abstract: Recently, there is a surge among people in choosing alternative systems of medicine, especially Siddha, over modern medicine. Hence, it is very much essential to standardise Siddha drugs as specified by World Health Organisation. In the present study, we carried out phytochemical analysis of Siddha drug formulation Arathai Kudineer Churnam. HPTLC finger printing profile was developed in addition to assessing total phenols and flavonoids. The formulation was also screened for its cytotoxic effects against HepG2 liver carcinoma cells. HPTLC fingerprinting along with quantitative determination suggests the presence of several key phytochemical components including phenols and flavonoid compounds. Arathai kudineer significantly inhibited the growth of HepG2 cells growth as well as depicted significant inhibition of free radicals in a dose dependent manner. Detailed studies will be conducted to characterise the bioactive components as well as elucidate the potential of Arathai kudineer to be used as a viable therapeutic agent.

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