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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Issue 1 (2019)

Molecular docking of embelin against human mono amine oxidase- a (MAO-A) enzyme

Author(s):

Nanthini B, Selvakumari E, Gopal V and Ranganadhan S

Abstract:
Vitiligo is a dermatological disorder. Free radical and reactive oxygen species are well known key factor for the pathogenesis of vitilgo. The present paper reports the formulation of poly herbal capsule, Molecular docking of embelin, a major constitution from the poly herbal capsule with the receptor mono amino oxidase-A enzyme and the in-vitro antioxidant activity of the poly herbal capsule by DPPH radical scavenging and total antioxidant assay method. The result showed the inhibitory effect of embelin against the receptor MAO-A. The in-vitro antioxidant activity of the formulated poly herbal capsule showed remarkable effect similar to the standard drug Ascorbic acid. The result obtained validates the traditional uses of the formulated poly herbal capsule in the treatment of vitiligo in siddha system of medicine.

Pages: 1642-1646  |  937 Views  285 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Nanthini B, Selvakumari E, Gopal V and Ranganadhan S. Molecular docking of embelin against human mono amine oxidase- a (MAO-A) enzyme. J Pharmacogn Phytochem 2019;8(1):1642-1646.

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