Abstract:
“Pashanbheda” is a well known Mutrasmarihara drug mentioned in Ayurvedic literature. It has various source plants being used in different region in India. Among them Bergenia ligulata Linn is considered as authentic source and due to over exploitation and specific habitat. It is enlisted as threatened. So it is essential to evaluate the source plants of Pashanabheda. The present study is taken up to evaluate Bryophyllum pinnatum Lam (Oken) a source plant of Pashanbheda used in Bengal. This study aims at comparative pharmacognostic evaluation of rhizome of Bergenia ligulata Linn and leaves of Bryophyllum pinnatum Lam (Oken).
Material and Method: Roots of Bergenia ligulata Linn was collected from Botanical garden of Godavari, Kathmandu Nepal. Leaves of Bryophyllum pinnatum Lam (Oken) collected from Herbal garden SDM College of Ayurveda and Hospital, Hassan Karnataka. Both roots of Bergenia ligulata Linn and Leaves of Bryophyllum pinnatum Lam (Oken) were subjected to macroscopic, microscopic, physicochemical, Preliminary phytochemical, and HPTLC evaluation as per standard method.
Result: 1 Alkaloids, steroids, carbohydrate, tannin, flavonoids, Saponine, Terpenoid, phenol and quenone are present in Bergenia ligulata Linn. 2) Steroids, carbohydrate, tannin, flavanoids, caumarins, amino acids and resin are present in Bryophyllum pinnatum Lam (Oken). 3) Maximum 11 peak present in HPTLC of ethanolic extract of both plant.
Conclusion: The pharmacognostic evaluatation reveals various chemical constituents that are common in both the drugs like steroids, Carbohydrates, Tannin and Flavanoids. Thin layer Chromatography reveal Rf value 0.4 in TLC.
Dr. Devraj KC, Dr. Anuradha KN, Dr. Santosh Poudel and Dr. Ashma KC. A comparative pharmacognostic evaluation of two source plants of pashanabheda Bergenia ligulata Linn. And Bryophyllum pinnatum lam (Oken). J Pharmacogn Phytochem 2019;8(1):2726-2732.