Objective: To explore the phenolic contents and antioxidant activity of the fruits and leaves of Spondias mombin (S. Mombin) grown in Bangladesh.

Method: Different solvents (Water, methanol, ethanol, acetone and n-hexene) were used for the extraction of fruits and leaves of S. Mombin. Polyphenolic contents and antioxidant activities were estimated by this crude extracts. Different in vitro methods were used for the investigation of antioxidant properties including phosphomolybdenum assay, DPPH free radical scavenging assay and reducing power assay.

Results: The study showed that the leaves and fruits contained saponin, steroid, tannin, alkaloid and flavonoid. Among the other extracts the methanolic extract showed the highest phenolic content, flaovonoid content and antioxidant activity. Fruits extracted with methanol showed the total phenolic content 719.25±0.94mg GAE/100gm of fresh weight and leaves extract showed the total phenolic content 161.36 ± 0.67 mg GAE/100gm of fresh weight.

Conclusion: The study recommended that Spondias Mombin exhibits significant polyphenolic activity and antioxidant activity and there is a strong correlation between phenolic content and antioxidant activity.