Journal of Pharmacognosy and Phytochemistry
Vol. 8, Issue 2 (2019)
Design, development and standardization of novel polyherbal syrup against renal calculi
Indumathy K, Selvakumari E and Gopal V
Renal calculi are the most common urinary disorder of urinary tract and its incidence is high throughout the world. Traditional practioners prescribe the whole plants of Tribulus terrestris
(Zygophyllaceae) and Aerva lanata
(Amaranthaceae) for the treatment of renal calculi. This study was aimed to design, develop and to characterize the novel polyherbal syrup using decoction of the whole plants of Aerva lanata
and Tribulus terrestris
and to evaluate its efficacy against renal calculi by in vitro
nucleation assay method. The formulated polyherbal syrup significantly inhibited nucleation of calcium oxalate crystals and the microscopical examination showed significant decrease in the number of calicum oxalate crystals for the standard drug cystone and formulated syrup. The result provides the scientific validation for the traditional uses of the herbal plants and the formulated novel polyherbal syrup might be an effective therapy for the management of urolithiasis.
Pages: 1859-1862 | 816 Views 335 Downloads
Indumathy K, Selvakumari E and Gopal V. Design, development and standardization of novel polyherbal syrup against renal calculi. J Pharmacogn Phytochem 2019;8(2):1859-1862.