Shailja, Pawan Jalwal, Priyanka Rani, Deepak, Jyoti, Ajit, Gourav, Sunil Kumar, Gurdev Singh and Sharad Sardana

Parkinson’s disease (PD) is a neurodegenerative disorder that affects predominately dopamine-producing (dopaminergic) neurons in a specific area of brain called substantia nigra and is marked by a combination of tremors, rigidity, impairment, slowness of movements, impaired balance, bradykinesia and shuffling gait. Curcumin being component of Curcuma longa is a natural polyphenol. Chemically, curcumin is a naturally polyphenol denominated (1E, 6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) which is extracted from the rhizomes of Curcuma longa. The objective was to formulate and evaluate curcumin loaded albumin nanoparticles. The studies done showed the spherical shape with smooth surface nanoparticles. The average particle size of F7 was found to be 226 nm and its Polydispersity index was 0.383.

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