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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Issue 3 (2019)

Evaluation of antioxidant potential and phytochemical characterization using GC-MS analysis of bioactive compounds of Achillea filipendulina (L.) leaves

Author(s):

Sana Khan, Richa, Harsimran Kaur and Rinku Jhamta

Abstract:
Achillea filipendulina (L.) is an important medicinal herb of family Asteraceae was investigated with aim to the screening of bioactive compounds present in its leaves. The qualitative test reveals the presence of alkaloids, flavonoids, terpenoids, glycosides, steroids, saponin and tannin. 31 bioactive compounds were identified from GC-MS analysis. Among the identified compounds, 13-Docosenamide, (Z) and 9-Octadecenamide was found to be the major compound. In vitro antioxidant scavenging activity was performed by DPPH assay and hydrogen peroxide assay showing the highest % inhibition of 92.98% and 82.02% as compared to standard respectively. Analysis of total phenolic and flavonoid content exhibited the presence of significant amount of phenolic content i.e. 261.77±0.54 mg/g and flavonoid 54.51±0.01 mg/g. Since the plant possess high content of phenols and flavonoids and also significantly high antioxidant scavenging activity it may have large number of pharmacological values. The results suggested the possible use of A. filipendulina for the development of highly potent, safe and novel antioxidant compounds.

Pages: 258-265  |  2662 Views  1471 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Sana Khan, Richa, Harsimran Kaur and Rinku Jhamta. Evaluation of antioxidant potential and phytochemical characterization using GC-MS analysis of bioactive compounds of Achillea filipendulina (L.) leaves. J Pharmacogn Phytochem 2019;8(3):258-265.

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