• Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Issue 3 (2019)

In vitro antidiabetic assessment of Ocimum forskolei L‏ ‏growing in Saudi Arabia

Author(s):

Hany Ezzat Khalil, Ali Gaber Ali Alharbi and Ibrahim Muhamed Ibrahim

Abstract:
The main objective of current study was to investigate the in vitro antidiabetic activity of Ocimum forskolei.In vitro antidiabetic assays such as inhibition of α-amylase enzyme, non-enzymatic glycosylation of hemoglobin were carried out.The results of α- amylase inhibition assay revealed that the inhibitory activity (IC50) of both leaves and stems methanol extracts are almost the same (72.3 and78.9µg/ml, for leaves and stems extracts, respectively) when compared with positive control (Acarbose IC50 value of 45.3µg/m). Regarding the inhibition of glycosylation of hemoglobin, inhibitory activity (IC50)both leaves and stems methanol extracts were (54.4 and‏ ‏‎70.3µg/ml, for leaves and stems extracts, respectively) when compared the positive control, alpha-tocopherol (35.4µg/ml). The results from this study indicated that Ocimum forskolei leaves and stems methanol extracts showed considerable in vitro antidiabetic activity.

Pages: 355-357  |  1025 Views  264 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Hany Ezzat Khalil, Ali Gaber Ali Alharbi and Ibrahim Muhamed Ibrahim. In vitro antidiabetic assessment of Ocimum forskolei L‏ ‏growing in Saudi Arabia. J Pharmacogn Phytochem 2019;8(3):355-357.

Important Publications Links
Journal of Pharmacognosy and Phytochemistry Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

Call for book chapter