Methods: The acute anti-inflammatory activity was studied by Carrageenan induced rat paw edema while chronic anti-inflammatory activity by cotton pellet induced granuloma model.

Results: The GC-MS analysis showed presence of 32 phytoconstituents. Among these 16 compounds which were previously reported for the presence of various biological activities. From the study, it was shown that the extract significantly inhibited paw volume in acute inflammation and weight of granuloma formation in chronic inflammation at both the doses in dose dependent manner.

Conclusion: From the results obtained, it was concluded that the C. bonducella extract possesses significant anti-inflammatory activity which validated its ethnopharmacological use in treatment of inflammation.