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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Issue 3 (2019)

Evaluation of antioxidant activities of methanol extracts and cassane diterpenoids from Erythrophleum suaveolens [(Guill. et Perr.) Brenan] (Fabaceae)

Author(s):

Konan Dibi Jacques, Attioua Koffi Barthélemy, Kablan Ahmont Landry Claude, Kabran Aka Faustin, Koua Kadio Brou Donald, Okpekon Aboua Timothée, Aka Any-Grah Sandrine, Sissouma Drissa and Koffi Agnély Armand

Abstract:
Erythrophleum suaveolens (Fabaceae), a medicinal plant from Côte d’Ivoire, was investigated for its antioxidant constituents. This led to the isolation of two cassane diterpenoid amides, 6a-hydroxy-nor-cassamide (1) and nor-cassamide (2), from the root barks. Their structures were established according to their spectroscopic analyzes (1D and 2D NMR, HR-ESIMS, IR). The antioxidant capacity of methanol extracts and isolated compounds were measured using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and the Ferric Reducing Antioxidant Potential (FRAP). A significantly increased DPPH and FRAP activities were observed for all samples. But, the best activity was obtained with methanol crud extract of the root barks from E. suaveolens (ESER).

Pages: 1051-1055  |  1045 Views  331 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Konan Dibi Jacques, Attioua Koffi Barthélemy, Kablan Ahmont Landry Claude, Kabran Aka Faustin, Koua Kadio Brou Donald, Okpekon Aboua Timothée, Aka Any-Grah Sandrine, Sissouma Drissa and Koffi Agnély Armand. Evaluation of antioxidant activities of methanol extracts and cassane diterpenoids from Erythrophleum suaveolens [(Guill. et Perr.) Brenan] (Fabaceae). J Pharmacogn Phytochem 2019;8(3):1051-1055.

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