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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 8, Issue 3 (2019)

In vitro antidiabetic and antioxidant activities of the methanolic extract of Alpinia purpurata root

Author(s):

Nivetha V, Subramaniyan V, Manikandan G, Divya Bharathi M, Krishna Prasanth T and Manjula K

Abstract:
In the present study the methanolic extract of root of Alpinia purpurata was studied for alpha amylase and alpha glucosidase inhibition using an in vitro model. The methanolic extract was also examined for its antioxidant activities by using free radical 1,1-diphenyl-2-picryl hydrazyl (DPPH) scavenging method. The study revealed that the different concentration of extracts exhibit potent radical scavenging activity using DPPH as substrate. The root of Alpinia purpurata exhibited significant α-amylase (66.10%) and α-glucosidase (78.70%) inhibitory activities at the concentration 100 µg/ml respectively and well compared with standard acarbose drug. Therefore, it is suggested that the methanolic extract of root of Alpinia purpurata is a potential source for natural antidiabetic and antioxidant compounds and could have potential use in the management of diabetes mellitus.

Pages: 1060-1064  |  2403 Views  1374 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Nivetha V, Subramaniyan V, Manikandan G, Divya Bharathi M, Krishna Prasanth T and Manjula K. In vitro antidiabetic and antioxidant activities of the methanolic extract of Alpinia purpurata root. J Pharmacogn Phytochem 2019;8(3):1060-1064.

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