Author(s):

Fifa T Diane Bothon, Lydia Abou, Ménonvè Atindehou, Kousséni Adam Yarou, Eben-Ezer BK Ewedje, Pascal CD Agbangnan, Latifou Lagnika, Emmanuel Wafo and Félicien Avlessi

Abstract: Ethanol extract and essential oil of Boswellia dalzielii leaves were screened for their antibacterial and antiradical activities by using microdilution and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical methods respectively. Ethanol extract was submitted to a phytochemical screening and the essential oil toGas Chromatography-Mass Spectrometry (GC/MS) analysis. Antibacterial studies reveal a MIC of 1.25 mg/ml for ethanol extract and 1.25 µl/ml of essential oil on Methicillin-resistant Staphylococcus aureus, but no MIC on Staphylococcus aureus. The essential oil was more powerful radical scavenging activity with EC₅₀ value of 1.25 μg/mL which greater than the standard antioxidants, ascorbic acid (EC₅₀ = 5 μg/mL). The phytochemical screening reveals the presence of metabolites mainly 3.56 ±0.06 mg GAE/ g of extract of total polyphenol and 1.24±0.01 mg QE/ g of extract. GC-MS results show the presence of: Zerumbone (33.69%), α-phellandrene (11.80%), alpha α-pinene (9.71%), Germacrene D (9.08%) ß - phellandrene (8.19%) and Trans ß – caryophyllene (7.45%) like major compounds. These compounds could be responsible for the antibacterial and scavenging activities.

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