Author(s):

Bidduth Kumar Sarkar, Subrato Kumar Barman, Sharmin Akhter, Rahima Akter, Joydeep Das, Arghya Prosun Sarkar, Rabeya Akter and Sukalyan Kumar Kundu

Abstract: The main objective of this work was to evaluate the in vitro anti diabetic activity of methanolic leaf extracts of two mangrove plants: Heritiera fomes and Sonneratia apetala. The selected leaf extracts were studied for their effect on inhibition of alpha amylase activity, glucose transport across yeast cells and glucose adsorption capacity. It was found that leaf extract of Heritiera fomes (HF) inhibited α-amylase more effectively than leaf extract of Sonneratia apetala (SA). HF leaf extract caused greater uptake of glucose by yeast cells than SA leaf extract at different concentrations. Glucose adsorption capacity of both leaf extracts was increased proportionately in a dose dependent manner. This investigation indicated that the selected plants possessed considerable in vitro anti diabetic activity. Found effects of this study need to be confirmed using in vivo models for its effective and safe therapeutic uses.

Pages: 2376-2380  |  858 Views  290 Downloads

Download (674KB)