Author(s):

Bhagwat Sameer Kisan and Sangita Ganguly

Abstract: The probiotic products are gaining importance in disease management and health restoration. The regular consumption of probiotic could offer a wide range of health benefits. Although, probiotics are considered as safe and beneficial for health and harmful effects of probiotic usage are rare, but recent data showed adverse effects of probiotic after long term consumption. Some medical reports specified that probiotic bacterias are rarely related with human opportunistic infections like sepsis, infective endocarditis, bacteraemia, urological infections, allergic sensitization and autoimmune disorders. Metabiotics are the structural components of probiotics, their metabolites or small signalling molecules whose chemical structure is known that can affect the human metabolic and signalling pathways. Metabiotics are advantageous over probiotic and synbiotic because of their known chemical structure, which can provide accurate information regarding their dosage, safety, and shelf-life. Metabiotics are a natural evolution and can be considered as future of functional food industry.

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