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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 9, Issue 2 (2020)

Isolation of 3, 5, 7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl) chromen-4-one from the stem bark of Lonchocarpus sericeus Poir. (Papilionaceae)

Author(s):

Uwemedimo Emmanuel Udo, Johnbull Onyekachi Echeme and Okenwa Uchenna Igwe

Abstract:
An O-methylated flavonol 3, 5, 7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl) chromen-4-one (isorhamnetin) was isolated from the dichloromethane fraction of the stem bark of Lonchocarpus sericeus Poir., (Papilionaceae), a medicinal plant widely employed in folkloric medicine in many communities in Southern Nigeria for the treatment of inflammation and pain. Its structure was established by a combination of spectroscopic techniques including FT-IR, 1HNMR, 13CNMR, 2-dimensional NMR spectroscopy, ESI-MS/MS and by direct comparison with literature values. This is the first report of the isolation of this compound from the plant L. sericeus.

Pages: 31-33  |  1460 Views  385 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Uwemedimo Emmanuel Udo, Johnbull Onyekachi Echeme and Okenwa Uchenna Igwe. Isolation of 3, 5, 7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl) chromen-4-one from the stem bark of Lonchocarpus sericeus Poir. (Papilionaceae). J Pharmacogn Phytochem 2020;9(2):31-33.

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