Author(s):

Gracyelle Guimaraes DE Carvalho, Geovana Correa Peres, Rafael Martins Custódio Mendonça and Edvande Xavier DOS Santos Filho

Abstract: The Brazilian biome Cerrado is a big source of obtaining plants for the research of new bioactive compounds with antibacterial potential. In this study, methanolic extracts of the leaves from Stryphnodendron adstringens (Mart) Coville and Solanum lycocarpum A. St-Hil; and ethanolic extracts of Anadenanthera falcata (Benth.) Speg. Stem and Cochlospermum regium (Mart. ex Schrank) Pilg. Tuberous roots were submitted to phytochemical prospecting and determination of antibacterial activity against four bacterial cultures Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa by the Kirby-Bauer method of plate diffusion. Diverse groups of secondary metabolites and some constituents were identified, suggesting bioavailability of alkaloids, anthraquinones, catechins, coumarins, steroids and triterpenoids, phenols and tannins, flavonoids, anthocyanins and anthocyanidins, flavonols, flavonones, flavanonols and xanthones, quinones and saponins. Likewise, all extracts presented antibacterial potential, especially Stryphnodendron adstringens (Mart) Coville extract at the concentration of 10 mg/mL against Escherichia coli and Staphylococcus aureus.

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