Author(s):

Balamurugan C, Karuppasamy R, Sivaraj C, Saraswathi K and Arumugam P

Abstract: Pomegranate (Punica granatum) is a wonder fruit because of its huge pharmacological properties. Pomegranate and its extracts exhibit potent anticarcinogenic properties and the waste part of this wonder fruit, pomegranate has miraculous effects for human health. The potential therapeutic properties are wide-ranging and include treatment and prevention for cancer, cardiovascular disease, diabetes, dental conditions, male infertility, arthritis, and protection from ultraviolet (UV) radiation. The objective of the study was to evaluate the Pomegranate leaves extract by in vitro antioxidant methods like DPPH^. radical, superoxide radical inhibition, phosphomolybdenum reduction, and ferric reducing power assays. The results showed that the Pomegranate leaves extract has significant antioxidant activity. The DPPH^. radical scavenging activity of leaves extract was 79.13±0.37% at 120 µg/mL concentration and its IC₅₀ was 39.16 µg/mL concentration. The superoxide radical scavenging activity of leaves extract was 71.48±0.43% at 120 µg/mL concentration and its IC₅₀ was 40.31 µg/mL concentration. The phosphomolybdenum (Mo⁶⁺) reduction of leaves extract was 53.36±0.39% at 120 µg/mL concentration and its RC₅₀ was 104.89 µg/mL concentration. The Fe³⁺ reduction of leaves extract was 81.47±0.13% at 120 µg/mL concentration and its RC₅₀ was 21.28 µg/mL concentration. The antibacterial activity showed the highest zone of inhibition of 19 mm against Micrococcus luteus.

DOI: 10.22271/phyto.2020.v9.i6f.12915

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