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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 10, Issue 2 (2021)

Medicinal applications of Euphorbia umbellata, as an antitumor agent, antiulcerogenic and other applications: Review

Author(s):

Monique Gonçalves Alves, Laertty Garcia de Sousa Cabral, Thais de Oliveira Conceição, Thalles Anthony Duarte Oliveira, Mercedez Reyes Hernández, José Artur Medina, Rosa Andrea NogueiraLaiso and Durvanei Augusto Maria

Abstract:
The demand for herbal medicines is steadily increasing. Within this perspective, compounds derived from the latex of the species Euphorbia umbellata have acquired a prominence presenting antiulcerogenic, anti-inflammatory, homeostatic activities and mainly antitumor activity. Studies carried out with tumor cells indicate that their fractions and subfractions act by modulating the apoptotic pathway by decreasing the mitochondrial electrical potential, as well as activating caspases 3 and 7. Concomitantly, its antiulcerogenic activity is related to the ability to capture radicals and species reactive oxygen, in addition to its inhibitory action in a peroxidase model. Other studies regarding other functionalities of this species are still in progress.

Pages: 29-35  |  503 Views  191 Downloads

How to cite this article:
Monique Gonçalves Alves, Laertty Garcia de Sousa Cabral, Thais de Oliveira Conceição, Thalles Anthony Duarte Oliveira, Mercedez Reyes Hernández, José Artur Medina, Rosa Andrea NogueiraLaiso and Durvanei Augusto Maria. Medicinal applications of Euphorbia umbellata, as an antitumor agent, antiulcerogenic and other applications: Review. J Pharmacogn Phytochem 2021;10(2):29-35. DOI: 10.22271/phyto.2021.v10.i2a.13669