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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 10, Issue 4 (2021)

Antioxidant and cytotoxic study of extract of vegetative and flowering stages leaves Stevia rebaudiana

Author(s):

Kulkarni AS, Dr. Deepali Karkhanis, Dr. SS Barve and Dr. Sweta Sharma

Abstract:

This study was performed to determine the anti-oxidant and in-vitro cytotoxic activity of Stevia rebaudiana plant extract collected during vegetative and flowering stages of plant against the commercial sweetener and Stevioside and Rebaudioside A standards. The anti-oxidant activity was determined by α, α-diphenyl-β- Picryl hydrazyl (DPPH) and Ferric reducing activity potential (FRAP) assay and cytotoxic activity by MTT assay. Flowering phase extract of Stevia showed greater antioxidant activity in FRAP assay. The in-vitro study was performed on 3 cell lines 3T3 cell line (murine), RAW cell line (murine) and MDA MB231 human cell line where the flowering stage extract showed 55% inhibition in cell growth.

Pages: 303-306  |  331 Views  120 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Kulkarni AS, Dr. Deepali Karkhanis, Dr. SS Barve and Dr. Sweta Sharma. Antioxidant and cytotoxic study of extract of vegetative and flowering stages leaves Stevia rebaudiana. J Pharmacogn Phytochem 2021;10(4):303-306.

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