• Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 10, Issue 5 (2021)

Effect of aqueous and methanolic extracts of Solanum aethiopicum Linn Gilo (Solanaceae) leaves on body weight and Glycemia in rats with alloxan-induced diabetes

Author(s):

Tuem SR, Ndomou M, Manz KJC, Nchoutpouen NM and Gouado I

Abstract:

The aim of this study was to evaluate effects of aqueous and methanolic leaves extracts of Solanum aethiopicum Linn Gilo on hyperglycemia and body weight in rats. Leaves were dried, crushed to obtain powder that were used to prepare extracts. The extracts underwent phytochemical screening and administered to alloxan diabetic transformed rats at 200 and 300 mg/kg body weight. Chemical analysis of extracts revealed presence of flavonoids, terpenoids, saponins, polyphenols, alkaloids, tannins and cardiac glycosides. Measurements of fasting blood glucose showed a hypoglycemiant effect of aqueous extracts which stood at -61.18% and -61.38% respectively for 200 and 300 mg/kg body weight against -59.50% and -60.60% for methanolic extracts. The reduction rate was -55.65% for glibenclamide, a reference antidiebetic drug. It could be concluded that aqueous and methanolic extracts of the leaves of Solanum aethiopicum Linn gilo, could be used to manage body weight under hyperglycemia and treatment of diabetes.

Pages: 142-146  |  454 Views  187 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Tuem SR, Ndomou M, Manz KJC, Nchoutpouen NM and Gouado I. Effect of aqueous and methanolic extracts of Solanum aethiopicum Linn Gilo (Solanaceae) leaves on body weight and Glycemia in rats with alloxan-induced diabetes. J Pharmacogn Phytochem 2021;10(5):142-146. DOI: 10.22271/phyto.2021.v10.i5b.14248

Important Publications Links
Journal of Pharmacognosy and Phytochemistry Pharmacognosy

Journal of Pharmacognosy and Phytochemistry

Call for book chapter