Girija PV, Renuka NK and Vijayan KK

Gulguluthikthakam kashayam is an excellent medicine for all types of inflammations especially pertaining to connective tissues, bones and joints. There are no prescription drugs that specifically target chronic inflammation. Now a days used nonsteroidal anti-inflammatory drugs carry side effects. Present study aims to identify the terpenoids present in the Gulguluthikthakam kashayam in order to confirm its efficacy. Volatile oil isolated from the kashayam using Clevenger apparatus and its chemical components determined with the help of GCMS. The compounds identified from the volatile oil of Gulguluthikthakam kashayam are Carvone, Beta-caryophyllene, Valencene, Cubenol, ar-Curcumene, Cedrol, Guaiol, Cembrene, Thunbergol, Guggulusterone, Mukulol and [6]-Paradol. The identified terpenoids found to have wide spectrum of biological activity so the synergistic effect between the different components present in the volatile oil may add its biological activity towards inflammation related diseases.

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