Rispa Johns, Arun OS and Dr. Sarala Samuel

The work aims to evaluate the bioactive study of Momordica dioica rox.ex willd by analysing antioxidant, anti-bacterial activity and cytotoxic effect. Separation of components using GC-MS analysis. Momordica dioica Fruit have good medicinal value and rich with number of phytoactives but not well explored. For its medicinal activity Momordica dioica Fruit is taken for this study and extracted its constituents sequentially using solvents of petroleum ether, chloroform, ethyl acetate, ethanol and distilled water. Phytochemical screening shows the presence of different phytoactives in different solvent extract. The GC MS study also proves the presence of therapeutically active component. DPPH activity and IC50 value prove the anti oxidant activity of the study material. Anti microbial activity revels the anti microbial activity against E.aerogenes, K.pneumoniae, S.aureus, E.coil, P.aeruginosa, proteus species and cytotoxicity effect proved by the In vitro cytotoxic study respectively.

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