Garvita Chaudhary Joshi and Meenakshi Bharkatiya

Some Polyherbal formulations containing Tinosporia cordifolia, Moringa oleifera and Allium sativum extracts were evaluated for its anti-inflammatory activity by in-vitro methods. Qualitative analysis of whole plant extract revealed the presence of alkaloid, flavonoid, saponins, steroid, phenol, tannin, glycoside and terpenoid. In-vitro anti-inflammatory activity of polyherbal formulations and individual extracts were estimated using membrane stabilization, antiproteinase activity, albumin denaturation assay, and antilipoxygenase activity at different concentrations. The results showed that polyherbal formulation showed significant results in all activities. Inhibition increased mostly with increasing the concentration. In membrane stabilization (HRBC assay) most active is PHF-3 while in albumin denaturation, Antiproteinase method and Antilipoxygenase assay highest activity is recorded with PHF-1. In vitro antiinflammatory activities were evaluated as the first study of inflammation for seeing the activities of polyherbal formulations. The study concluded that the PHF-1 is potent among all the formulations as it showed a better antiinflammatory activity as compared to other formulations.

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