Desai Swapnil Rajesh Kumar, Dr. Monimala Pramanick, Dr. Suraj Singh Bhadoria and Dr. Poorav Desai

Background: To compare the Hypericum perforatum liniment prepared by Hypericum perforatum mother tincture in olive oil at different drug and vehicle ratio under the quality assessment by UV- Visible Spectroscopy and FTIR (Fourier Transform Infrared Spectroscopy).

Methodology: In this process preparing the Liniment from Standard Hypericum perforatum- Q, which was taken from pharmaceutical company and mixed in the olive oil as a baseline sample. Samples were prepared by measuring the quantity first, mixing, filling and finally labelling. Samples were divided into three groups; such as standard group, sample group and control group. All these samples were passed under the UV-Visible Spectrophotometer and FTIR (Fourier-Transform Infrared Spectroscopy).

Conclusion: After Data analysis, it was found that absorbance value of Hypericum perforatum liniment prepared in (1:4) drug and vehicle ratio gives better results in analysis done by UV- Visible Spectrophotometer and FTIR (Fourier Transform Infrared Spectroscopy) as compare to other drug and vehicle ratio i.e. (1:1) and (1:9).

Whereas in FTIR, the maximum transmission is brought on (1:1) as compared to the other drug and vehicle ratio i.e. (1:4) and (1:9).

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