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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 12, Issue 2 (2023)

Phytochemical screening, phenolic determination and antibacterial activity of the extracts of Bridelia scleroneura Muell. Arg. (Euphorbiaceae) from Chad

Author(s):

Nodjitoloum Mborbe, Mahamane Idi Issa Abdoulahi, Mbaiogaou Abel, Hama Hamadou Habibou and Mahmout Yaya

Abstract:

Bridelia scleroneura Müll. Arg. is traditionally used in the southern part of Chad to treat diabete, hypertension and anemia. This study reports the chemical composition of B. scleroneura leaves, barks twigs extracts and their polyphenols contents and also their antibacterial activity. Phytochemicals were assessed by phytochemical screening and spectrophotometry. The microdilution method was used to evaluate the antibacterial activity of extracts against Staphylococcus aureus (ATCC25923 /ATCC43300), Streptocococcus pneumonia (ATCC461916), Pseudomonas aeruginosa (HM801), Klebsiella pneumonia (clinical isolate), Salmonella typhi (clinical isolate) and Eschierichia coli (clinical isolate). The extracts showed the presence of alkaloids, saponins, terpenes, steroids, polyphenols, tannins, quinones and flavonoids. The flavonoid content is higher in the leaves, tannin and polyphenol contents are higher in the barks. The antibacterial tests indicated that the bark extract exhibited a significant activity on Staphylococcus aureus.

Pages: 44-47  |  817 Views  393 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Nodjitoloum Mborbe, Mahamane Idi Issa Abdoulahi, Mbaiogaou Abel, Hama Hamadou Habibou and Mahmout Yaya. Phytochemical screening, phenolic determination and antibacterial activity of the extracts of Bridelia scleroneura Muell. Arg. (Euphorbiaceae) from Chad. J Pharmacogn Phytochem 2023;12(2):44-47. DOI: 10.22271/phyto.2023.v12.i2a.14629

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