Dr. Md. Shohidul Islam

The research aimed to know the anti-microbial activity of the methanolic extract of Senna alata leaves. A disk diffusion method was used to estimate the antimicrobial activity of Senna alata leaves extract to Escherichia coli, Streptococci pyogenes, and Proteus mirabilis by demonstrating a Zone of inhibition. The extract of Senna alata leaves containing paper disk inhibited the growth of pathogenic bacteria. Paper disks containing 25, 50, 75, and 100 µg showed 10, 15, 20, and 28 mm zone of inhibition against E. coli. Resistance, 9, 14, and 19 mm zone of inhibition against S. aureus. 08, 11.5, 15, and 21 mm zone of inhibition against Klebsiella pneumiae. Resistance, 8, 5, 10, and 16 mm zone of inhibition against Pseudomonus aeroginos and Resistance, 12 and 16 mm zone of inhibition against Pseudomonus. It concluded that proper and systemic study of Senna alata may become the raw material of natural origin for antimicrobial drug production.

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