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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 12, Issue 3 (2023)

Phytochemical profile and antiradical and antidiabetic activities of a plant recipe known to be antidiabetic in traditional Congolese medicine

Author(s):

Koubaka Jean Francy Ystaelle, Bonazaba Milandou Longin Justin Clair, Babouongolo Sévère-Grébel, Nkounkou Loumpangou Célestine and Tony Malaissou Dhornycia Euroldyne

Abstract:

The aim of this work is to promote traditional Congolese medicine. Thus, a plant recipe known to be anti-diabetic, called "NGOSI" was used for a chemical and biological study. Phytochemical screening and antiradical activity of the recipe were carried out by TLC on the different fractions (chloroformic, methylethylketone and ethanolic) of this recipe. The anti- diabetic activity was evaluated by monitoring the glycaemia of rats made hyperglycaemic by oral glucose at a rate of 3 g/kg, and of rats made diabetic by injection of alloxane. The results obtained confirm the efficacy of the recipe with a percentage reduction in the average blood glucose level of the rats of 68.03% (p < 0.01). The screening results showed the presence of several metabolites (terpenes, sterols, flavonoids, saponosides, glycosides and sugars). The screening of the antiradical activity of this recipe was positive on TLC. These results justify the use of this recipe in the traditional treatment of diabetes.

Pages: 37-42  |  461 Views  214 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Koubaka Jean Francy Ystaelle, Bonazaba Milandou Longin Justin Clair, Babouongolo Sévère-Grébel, Nkounkou Loumpangou Célestine and Tony Malaissou Dhornycia Euroldyne. Phytochemical profile and antiradical and antidiabetic activities of a plant recipe known to be antidiabetic in traditional Congolese medicine. J Pharmacogn Phytochem 2023;12(3):37-42.

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