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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 12, Issue 6 (2023)

Evaluation of the in vitro and in vivo antioxidant activity of aqueous and hydroethanolic extracts of Harungana madagascariensis trunk scores

Author(s):

Oumar Koné, Gneho Doh Arioste Delchinor, N'Guessan Assieoussou Jean-Luc, Yeo Dodehe and Trebissou Jonhson Noel

Abstract:

Harungana madagascariensis (Hypericaceae) is a plant traditionally used by the people of Côte d'Ivoire and West Africa to treat malaria and gastrointestinal complications. With a view to enhancing the value of Ivorian plants, the antioxidant activity of aqueous and hydroethanolic extracts of the plant's stem bark were assessed in vitro and in vivo. The polyphenols in the various extracts were quantified spectrophotometrically, and the in vitro and in vivo antioxidant activity was assessed using DPPH, FRAP, TBARS and total antioxidant power tests. Quantification of the polyphenols showed that the hydroethanol extract was richer (429.6±17.11 mg EAG/g) than the aqueous extract (307.7±31.83 mg EAG/g). With regard to antioxidant activity in vivo, the hydroethanol extract had the best activity than vitamin C. However, the aqueous extract showed the best antioxidant activity in vivo and was close to that of ascorbic acid. 

Pages: 137-142  |  131 Views  65 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Oumar Koné, Gneho Doh Arioste Delchinor, N'Guessan Assieoussou Jean-Luc, Yeo Dodehe and Trebissou Jonhson Noel. Evaluation of the in vitro and in vivo antioxidant activity of aqueous and hydroethanolic extracts of Harungana madagascariensis trunk scores. J Pharmacogn Phytochem 2023;12(6):137-142. DOI: 10.22271/phyto.2023.v12.i6b.14776

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