Abdullahi M Abdullahi, Sani M Isyaka and Ahmad N Suleiman

Croton nigritanus is a member of the Euphorbiaceae family, which has about 1,300 species worldwide and is found in tropical climates. Many of these species have a long history of use as medicines in South America, Asia, and Africa. They have been used to cure a variety of illnesses, including malaria, ulcers, diabetes, constipation, and cancer. In this study, it was determined what new molecular structures were present in the compounds taken from Croton nigritanus leaves from Kaduna, Nigeria. The procedure involves liquid-liquid extraction using n-hexane and dichloromethane as solvents through the partition method, followed by solid-liquid extraction utilizing the maceration method with dichloromethane as the solvent. Thin-layer chromatography and gravity column chromatography (GCC) were used for separation and purification. FTIR and 1HNMR spectroscopy were used to identify the isolated chemical. The present compound was effectively isolated and examined in the investigation. Furthermore, Croton nigritanus crude extract shown action against both Yeast and A. niger, indicating its potential for treating a variety of fungal illnesses that impact living things.

DOI: 10.22271/phyto.2024.v13.i1a.14810

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