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Journal of Pharmacognosy and Phytochemistry

Journal of Pharmacognosy and Phytochemistry

Vol. 13, Issue 2 (2024)

Effect of methanolic and ethyl acetate extracts of the rhizomes of Curcuma mangga acclimated to Congo on the production of reactive oxygen species (ROS)

Author(s):

Kévin Bikindou, Ernest Bitemou, Ghislaine Boungou-Tsona, Houzel-Mampouty Bounkosso, Jaynereuse P Nombault Nienzi and Aubin Nestor Loumouamou

Abstract:

The effect of extracts from acclimated C. mangga rhizomes from Congo on the production of reactive oxygen species (ROS) was evaluated on leukocyte cells obtained by hemolysis of human blood. Two types of extracts were tested, the methanolic extract and the ethyl acetate fraction. The results show that both extracts significantly reduce the production of ROS. However, the extract obtained with ethyl acetate is more active with an inhibition percentage of 63%, compared to the methanolic extract which inhibits it by up to 55%. This significant activity of the ethyl acetate extract would be linked to the major compounds identified in this extract, namely Zerumin A and (E)-labda-8(17), 12-dien-15, 16- dial.

Pages: 781-786  |  85 Views  35 Downloads


Journal of Pharmacognosy and Phytochemistry Journal of Pharmacognosy and Phytochemistry
How to cite this article:
Kévin Bikindou, Ernest Bitemou, Ghislaine Boungou-Tsona, Houzel-Mampouty Bounkosso, Jaynereuse P Nombault Nienzi and Aubin Nestor Loumouamou. Effect of methanolic and ethyl acetate extracts of the rhizomes of Curcuma mangga acclimated to Congo on the production of reactive oxygen species (ROS). J Pharmacogn Phytochem 2024;13(2):781-786. DOI: 10.22271/phyto.2024.v13.i2f.14923

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