Chaitra S Shriyan, Iravati J Chengalur and Vishal Banewar
Quercetin, a naturally occurring common dietary flavonoid, is mainly found in vegetables, fruits and other plants. It can regulate cellular signaling pathways related to disease progression. Quercetin is known to have a plethora of activities, ranging from anti-oxidant, anti-inflammatory, antibacterial, among others. But its medicinal potential is hindered because of it low bioavailability and limited selectivity due to poor water solubility and permeability. This study aims at synthesizing semi-synthetic derivatives of quercetin with a view to improve its bioavailability.
Fig. 1: Comparative UV plot of 1, 1a, 1b andn1c
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