Sajeena CH, Fidha Naseem, Dhilsha KP, Muhammed Jauharudheen PP, Muhammad Salih CK, Sabreen Varikkodan, Celestin Baboo RV, and Sirajudheen MK

Premna Serratifolia is a medicinal shrub most widely used in traditional remedies across India and Southeast Asia. The generic name is derived from the Greek word “premnon” meaning tree stump, referring to the often short and twisted tree trunks of i. In the Indian traditional Ayurvedic system of medicine the plant is a highly valuable ingredient of Dashamoolam. The goal of this review is to assess the current progress of research on Premna Serratifolia. This review focuses on bioactive compounds, in vitro activities Premna Serratifolia. The most frequent used solvents are water, methanol and ethanol. The information on bioactive compounds is mainly from methnol and ethanol extract. Various bioactive compounds like oleanolic acid, diosmin, and terpenoids. These findings provide strong support for the traditional use of Premna Serratifolia and highlight its potential as a source of natural therapeutic agents. Nonetheless, further in-depth pharmacological investigations and clinical validations are essential to fully establish its efficacy, safety, and mechanisms of action.Premna Serratifolia is a medicinal shrub most widely used in traditional remedies across India and Southeast Asia. The generic name is derived from the Greek word “premnon” meaning tree stump, referring to the often short and twisted tree trunks of i. In the Indian traditional Ayurvedic system of medicine the plant is a highly valuable ingredient of Dashamoolam. The goal of this review is to assess the current progress of research on Premna Serratifolia. This review focuses on bioactive compounds, in vitro activities Premna Serratifolia. The most frequent used solvents are water, methanol and ethanol. The information on bioactive compounds is mainly from methnol and ethanol extract. Various bioactive compounds like oleanolic acid, diosmin, and terpenoids. These findings provide strong support for the traditional use of Premna Serratifolia and highlight its potential as a source of natural therapeutic agents. Nonetheless, further in-depth pharmacological investigations and clinical validations are essential to fully establish its efficacy, safety, and mechanisms of action.

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