Priyanka Marotirao Yelgandhalwar and Deepali J Amale

Ayurveda describes Jwara as a disease of immense importance, affecting body, senses, and mind. Among its three stages Sama, Pachyamana, and Nirama the differentiation between Sama and Nirama avastha holds diagnostic and prognostic significance. Dengue fever, a mosquito-borne viral illness caused by Aedes aegypti, presents with high fever, myalgia, anorexia, and systemic inflammation. C-reactive protein (CRP), an acute phase reactant, is a marker of systemic inflammatory activity. This observational literary study aimed to correlate the Ayurvedic understanding of Aamapachyamanadi Jwara Avastha in dengue fever with CRP levels. Forty clinically diagnosed dengue patients were assessed for Sama and Nirama avastha symptoms along with CRP measurements. Findings indicated higher CRP levels during Sama Avastha, when disease activity is greater, and lower levels during Nirama Avastha, reflecting recovery. This suggests a possible scientific basis for the Ayurvedic concept of disease stages and their correlation with biochemical markers.

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