Kumbha Prathyusha, Poli Sai Padma Priya, Koppula Jaya Nissi, Kolasani Venkata Ramaiah, Mangalapudi Rami Reddy and Mamillapalli Mohan Krishna

This study evaluates the phytochemical composition and antimicrobial activity of Crinum asiaticum leaf extract for developing herbal hand wash tablets. Ethanolic extraction followed by qualitative screening confirmed the presence of alkaloids, flavonoids, tannins, phenols, glycosides, and saponins. The extract was tested against E. coli, Bacillus subtilis, and Aspergillus niger using the agar well diffusion method, showing clear, concentration-dependent zones of inhibition. A herbal hand wash tablet was formulated using the extract and assessed for pH, appearance, foamability, viscosity, and skin irritation, all of which met acceptable standards. The formulation displayed strong antimicrobial action comparable to marketed products. Overall, Crinum asiaticum extract demonstrates promising potential as a natural and effective antimicrobial ingredient for herbal hand wash tablets.

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