Author(s):

Sheetal G Roy, Namrata S Shirsat, Ashish C Mishra, Sandeep O Waghulde and Mohan K Kale

Abstract: Chitosan is a polymer naturally obtained by deacetylation of chitin. It is a polymer which is biodegradable and biocompatible regarded as safe for human dietary use and also approved for wound dressing applications. Because of their better stability, low toxicity, simple and mild preparation method and providing versatile routes of administration, chitosan nanoparticles have gained more attention as drug delivery carriers. Nanoparticles (NP) are prepared with chitosan and its derivatives possess a positive surface charge and mucoadhesive properties such that can adhere to mucus membranes and release the drug payload in a sustained release manner. Their sub-micron size is suitable for various applications in non-parenteral drug delivery for the treatment of cancer, gastrointestinal diseases, pulmonary diseases, drug delivery to the brain and ocular infections.

DOI: 10.22271/phyto.2018.v7.isp6.1.01

Pages: 01-04  |  3071 Views  1100 Downloads

Download (476KB)